Premature babies (build up of acid levels in blood)

 

The BASE study is looking at the use of a medicine called sodium bicarbonate in preterm babies in metabolic acidosis. Metabolic acidosis is a build up of acid in the blood.

 

What is the study about?

The study is looking at the use of a medicine called sodium bicarbonate in preterm babies in metabolic acidosis. This is when the blood PH drops and there is a build up of acid in the blood which can occur when a baby is unwell.

 

Who can take part?

Parents of babies born 23-30+6 weeks gestation will be given an information leaflet.

 

What is involved

If a parent gives verbal consent for the study and the baby has an episode of metabolic

acidosis. Babies will be allocated to be given, either a medicine called sodium bicarbonate or

not be given the sodium bicarbonate, depending on which arm of the study that the baby is

allocated. Other than this, all aspects of their care will be exactly the same as routine care,

including treating any known causes of metabolic acidosis.

 

If the baby is allocated to be not given sodium bicarbonate. Sodium bicarbonate can be given

if the clinician feels that it is appropriate. Some babies may not go on to develop metabolic

acidosis, therefore will not be included in the research study, even if parents had verbally

consented.

 

There is no payment for taking part in the study. However, when the trial centre send a

questionnaire when your baby is 2 years old. You will be sent a £15 high street voucher to

compensate you for your time.

 

How do I take part?

Parents will be approached by the nurses or doctors and / or the research nurses.

Please also ask the doctors and nurses looking after your baby, if you would like to know more.

 

Tell me more

For more information visit the study website.