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Wirral University Hospital NHS Foundation Trust

Surgery

Kidney cancer surgery

About

The PARTIAL study is a research study looking at the long term impact on function of the kidney between two types of surgery for kidney cancer.

 

The study will compare two different types of surgery:

  • Removal of the whole kidney, known as total nephrectomy, or
  • Removal of part of the kidney, known as partial nephrectomy.

 

Which surgery will I have?

You will be randomly allocated to one of the two surgical treatments.

 

Who can take part?

Eligible patients will be approached by their doctor at their clinic appointment.

 

More information

For more information please visit the study website. [external]

Antibiotics before bowel surgery

Patients who have surgery on their bowel can develop infections in their wound.

This study is comparing two ways of giving antibiotics before bowel surgery, to see if one way is better than another at preventing infections after the surgery.

Eligible patients may be approached prior to their surgery or on the day of their surgery.

Antibiotic treatment for abdomen infections

About

The EXTEND study is looking at the antibiotic treatment of patients treated for serious abdominal infections.

The study aims to see if a fixed 28 day duration of antibiotics is overall better for treating patients with serious abdominal infections than shorter courses of antibiotics as decided by a doctor.

 

Eligible patients may be approached while they are an inpatient on the ward.

Prostate cancer

Evaluation of Lymphadenectomy In High Risk Prostate Cancer Surgery

About

This study is looking at two different types of surgery for patients with high-risk localised prostate cancer.

If you take part, you will be randomised (toss of a coin) into either receiving:

  • Removal of the prostate with removal of lymph nodes
  • Removal of the prostate without removal of lymph nodes

 

How do I take part?

You will be approached by your doctor or research nurse during your pre-operative appointments.

 

For more information:

Visit the trial website here. [external]

Retinal repair

COMBAT trial logo

About

The retina is the layer at the back of the eye that gives sight. Normally it is attached to the wall of the eye, but it can separate in a condition called rhegmatogenous retinal detachment (RRD). RRD causes sight loss and requires surgery. 

The most common surgery to treat RRD is vitrectomy. Depending on how bad the RRD is, a single operation may put the retina back in place in around 8 in 10 eyes. 

Vitrectomy can have complications. The most common is cataract. A cataract is when the lens of the eye, normally clear, becomes foggy. Cataracts often get worse with time. When they affect vision, they need to be removed with surgery. In cataract surgery, the foggy lens is replaced with an artificial clear lens. Patients with RRD may already have an early cataract, especially if they are older than 50 years. Surgeons do not routinely offer cataract surgery at the same time as vitrectomy in people with RRD. So, most often, when the cataract gets worse after the vitrectomy, cataract surgery is offered at that time.

COMBAT trial will test whether it is better to continue to do the vitrectomy alone when repairing the RRD or whether it may be better to do both the cataract surgery and the vitrectomy surgery at the same time, in one single operation.

 

How do I take part?

You will be approached by our research team during your pre-operative assessment if you are eligible.